Deaths By VAX Code – Weighted

Exploratory data analysis

Of those the DIED post vaccination, which vaccines were given, weighted by the number of reactions for each vaccine?

Field Analysis:

Because the average number of vaccines given per VAERS_ID is not one, but greater than one, the resulting total numbers for DIED and Reactions are larger than found in the single table VAERSDATA.

For details, see the field analysis in:

Deaths By VAX Code

Also, Normalized Table AD_2019_ALL_VAX_NORM

Query:

SELECT vax.VAX
, count ( DIED )  Count_VAX_DIED
, Count(*) Count_Reactions
, 100.0 * count ( DIED )  / Count(*) 
   as PCT_DIED_Per_Reactions
From dbo.[VAERSDATA]  v
JOIN   dbo.[AD_2019_ALL_VAX_NORM] vax
   on   V.VAERS_ID = VAX.VAERS_ID
Group by vax.VAX
order by 4 desc

 

Results 1:

Results are ranked in descending order, according the largest percent weight of DIED, given the number of Reactions.

Only the 21 rows with 3% or more.

VAXCount_VAX_DIEDCount_ReactionsPercent Weight
BCG9858416.78082
DTPHEP4429315.01706
PLAGUE32810.71429
HPVX991,9115.18053
MEA387724.92228
DTPIPV326534.90046
6VAX-F2134,4684.76723
RVX621,4584.25240
MNC51194.20168
DTPHIB2666,3624.18108
OPV1,03324,7974.16583
DTPIHI61484.05405
PER71823.84615
DTP87723,6383.71013
DTAPHEPBIP39410,7393.66887
PNC10184963.62903
HBHEPB1965,5783.51380
PNC97428,0403.47361
HBPV92603.46154
RV12638,1013.24651
HIBV1,73954,8563.17012
DTAPIPVHIB2879,9692.87892

Results 2:

Results are ranked in descending order, according to the number of Reactions. Results are separated into 3 groups:

Reaction count of 10k or more (Large set)
Reaction count from 1k to 10k (Mid size set)
Reaction count less than 1k (Small set)

VAXCount_VAX_DIEDCount_ReactionsPercent Weight
OPV1,03324,7974.16583
DTP87723,6383.71013
DTAPHEPBIP39410,7393.66887
PNC97428,0403.47361
HIBV1,73954,8563.17012
PNC1383433,5942.48259
FLUX53324,0092.22000
RV545420,7852.18427
IPV82841,7271.98433
HEP1,31167,5321.94130
DTAP86860,4691.43545
FLU387496,883.90212
PPV54162,381.86725
HPV436845,370.81111
FLU412624,056.52378
MMR41082,369.49776
HEPA11737,584.31130
MNQ6623,160.28497
VARZOS19973,071.27234
HPV93112,763.24289
TD4218,150.23140
VARCEL17677,801.22622
TDAP7838,174.20433
MMRV2414,782.16236
    
HPVX991,9115.18053
6VAX-F2134,4684.76723
RVX621,4584.25240
DTPHIB2666,3624.18108
HBHEPB1965,5783.51380
RV12638,1013.24651
DTAPIPVHIB2879,9692.87892
RAB1315,1182.55959
MEN804,2051.90250
FLUX(H1N1)502,6681.87406
UNK975,8661.65360
FLUA3372,3921.54682
YF613,9771.53382
DT252,608.95859
FLU(H1N1)859,175.92643
HPV2424,563.92045
TTOX273,519.76726
HEPAB285,131.54570
MENB438,499.50594
LYME92,226.40431
FLUN3256,412.38989
FLUN4153,925.38217
TYP328,496.37665
ANTH319,030.34330
DTAPIPV309,270.32362
SMALL185,678.31701
FLUN(H1N1)92,892.31120
FLUC331,075.27907
FLUC453,346.14943
    
BCG9858416.78082
DTPHEP4429315.01706
PLAGUE32810.71429
MEA387724.92228
DTPIPV326534.90046
MNC51194.20168
DTPIHI61484.05405
PER71823.84615
PNC10184963.62903
HBPV92603.46154
TDAPIPV31152.60870
MM31162.58621
JEVX31202.50000
MENHIB62422.47934
MU52032.46305
TBE31322.27273
DTAPH158551.75439
DTPPHIB31841.63043
RV107011.42653
DTIPV53531.41643
MER32151.39535
JEV5566.88339
DTOX1121.82645
ADEN_4_71134.74627
DPP1215.46512
JEV12460.43478
CHOL1232.43103
FLUR42926.21598
RUB1938.10661
FLUR30194.00000
HEPATYP037.00000
MUR032.00000
MNQHIB022.00000
SSEV012.00000
ADEN011.00000
CEE011.00000
DF05.00000
H5N104.00000
DPIPV02.00000
    
Total15,4991,155,3411.342
Rows92 

Summary Statistics:

Total VAX Given To DIEDPercent Weight of Total DIEDCount of rows
Large set12,89783.224
Mid Size2,26914.629
Small set3332.139
    
Total15,499100

Total ReactionsPercent Weight of Total Reactions
Large set996,73086.3
Mid Size147,91812.8
Small set10,6930.9
   
Total1,155,341100

Total VAX Given To DIEDTotal ReactionsPCT_DIED_Per_Reactions
Large set12,897996,7301.29
Mid Size2,269147,9181.53
Small set33310,6933.11
    
Total15,4991,155,3411.34

 

Analysis:

The number of individual rows in VAERSDATA:
n=759,483

The number of all vaccines given:
n=1,155,341

DIED:

The number of individuals who DIED in VAERSDATA:
n=8,150

Count of vaccines given to DIED:
n=15,499

Of the 92 VAX codes, 82 had at least one death.

The 10 VAX codes with zero post vaccination deaths are: FLUR3, HEPATYP, MUR, MNQHIB, SSEV, ADEN, CEE, DF, H5N1, DPIPV

Of the 10 VAX codes that did not have any deaths, all had very few reactions. 9 of the 10 VAX codes only recorded 37 or fewer reactions in the VAERS dataset. The 10th VAX code, FLUR3, had only 194 reactions.

Summary Statistics Tables:

Looking at the summary statistics of the different size sets, the large set (10k reactions or more) had 86% of all reactions, but only 83% of all deaths.

The Mid size set (1k to 10k reactions) accounted for 12% of all reactions, but 14% of all deaths.

The small set (1k reactions or less) accounted for .9% of all reactions, but 2.1% of all deaths.

In the third aggregate table, PCT_DIED_Per_Reactions shows the per capita death rate between sets. The large set had only 1.29% DIED per their reactions in the set. However, the small set had 3.1% DIED per their reactions.

This could indicate that historically, if vaccines were noted to have a higher death rate, they might have been taken off the market for safety reasons. If anyone knows about the history of these lesser used VAX, with higher post vaccination deaths, please leave a comment.

Variability Of Per Capita Rates of Post Vaccination Deaths:

The per capita percent of post vaccination deaths, varies widely.

The VAX code with the most per capita deaths post vaccination is BCG. BCG counts 98 DIED in only 584 reactions, giving a post vaccination death rate of 16.7%. This is approximately 1 death for every 6 BCG reactions.

The VAX code with the least per capita deaths post vaccination is RUB. RUB counted only 1 DIED in only 938 reactions, giving a post vaccination death rate of only .10661% per RUB reaction. This is about 1/10th of 1%.

Both of these VAX codes are found in the small set.

This is huge variation between the min (0.1%) and the max (16.7%).

The multiples between the min and max rate in the small set are
= 16.7% / 0.1%
= 157 times

In the mid size set, the VAX code with the smallest per capita post vaccination deaths is FLUC4. The deaths are only .14943% of all reactions. About 1/7th of 1%.

In the mid size set, the VAX code with the highest per capita post vaccination deaths is HPVX. Deaths are found 5.1% of all HPVX reactions. For every 20 reactions, there was about 1 death.

The multiples in variability between min and max are:
= 5.1% / 0.149%
= 34.6 times

In the large set, the VAX code with the smallest per capita post vaccination deaths is MMRV. Deaths are found in .16% of all OPV reactions. About 1/6th of 1%.

In the large set, the VAX code with the highest per capita post vaccination deaths is OPV. Deaths are found in 4.1% of all OPV reactions. For every 25 reactions, there was about 1 death.

The multiples in variability between min and max are:
= 4.16% / 0.16%
= 25 times

There is a huge variability of post vaccination deaths rates between different vaccines.

Some vaccines have had a lot more per capita post vaccination deaths than other others.

 

 

 

 

 

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